Real Results, Real Impact
Work
See how we've helped our clients achieve remarkable results.
ACNU Pathway
Safer, simpler paths to self-care.
Success Story
Rx-to-Nonprescription Switch: TACTiC Trial ’24
In AstraZeneca's Technology-Assisted Cholesterol Trial in Consumers (TACTiC), our device successfully demonstrated that participants could:
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Safely and effectively self-select, acquire, and use rosuvastatin calcium 5-mg over six months.- Manage statins using technology-assisted self-management tools.
Self-Selection
Actual Use
Adherence
LDL Reduction
TACTiC trial results · rosuvastatin calcium 5-mg · six months
Success Story
Clinical Trial Recruitment
Actual Use Study
We managed paid search, paid social, display, landing-page strategy and development, and recruitment performance across campaigns and vendors. Continuous monitoring revealed which sources were enrolling participants, allowing us to invest more in what worked and less in what did not. The result: faster, more efficient recruitment.
Participant Enrollment Tracking
Ahead of projected enrollment
Of participants enrolled digitally
Visibility
Earn visibility wherever decisions begin.
Success Story
Rare Disease Campaign
We delivered a comprehensive paid-search audit and reengineered the account structure for a leading pharmaceutical client, systematically closing the performance gaps their AOR had overlooked.
- 73% increase in connecting patients to the care they needed (conversions)
- 45% reduction in advertising costs (cost-per-click)
Success Story
AI Search Readiness
We have always treated organic and paid search as one connected system, built around what people need to know. That meant investing early in the signals that endure: relevance, clarity, and authority. It meant preparing brands for a search landscape that would extend beyond blue links into zero-click results. So, when AI Search arrived, our clients organically evolved. Their brands were already structured to be understood, trusted and discovered. Despite fewer sessions, we saw higher engagement.
- 55% increase in HCP referral form downloads through organic search
- 42% increase in sign-ups across total search (organic + paid)
Organic Search
HCP Sessions
DTP Sessions
DTP Engagement
HCP RF Downloads
Total Search (Organic + Paid)
HCP Sessions
DTP Sessions
Engagement
RF Downloads
Sign-Ups
YoY comparison · January – November · 2024 vs 2025
Success Story
Reframing Language for AI Search Visibility
Patients validate treatment decisions through “review” searches, but MLR policies prohibit that terminology on brand sites. We deployed a Semantic Bridge to make compliant content visible to AI search engines without introducing compliance risk.
Challenge → Solution → Outcome
Patients search “[brand] reviews”. MLR prohibits that language on brand sites. AI defaults to unregulated forums.
Reframed non-compliant nouns into compliant CTAs through page optimization & structured data, so AI recognizes content as satisfying “review” intent.
Brand video content now appears in AI-generated answers for “review” queries, displacing forum content.
Results
AI Visibility Unlocked
Brand video content now surfaces in AI-generated answers for 'review' queries, displacing unregulated forum content.
Validation Moment Owned
The brand now controls the critical treatment-validation touchpoint in the patient journey.
Full MLR Compliance
Zero compliance risk: no implied claims, no solicitation of unverified reviews. Fully MLR safe.
Engagement period · November 2025
Success Story
Driving Cost-Effective HCP Engagement with PPC
We restructured an underperforming paid search account to reach prescribing physicians with precision, dramatically improving engagement while cutting acquisition costs.
Click-Through Rate
Cost Per Click
Challenge → Solution → Outcome
Existing PPC campaigns used broad, therapeutic keywords that attracted the wrong audience: patient traffic instead of prescribing HCPs. High spend, low engagement.
Restructured campaigns around HCP-intent keyword clusters, deployed prescriber-specific ad copy, and layered NPI-list targeting to ensure only qualified physicians saw the ads.
CTR surged 147% while CPC dropped 41%, proving that precision targeting compounds into both better engagement and lower cost.
Results
147% Higher CTR
Physician engagement with ads more than doubled through precision keyword targeting and HCP-specific copy.
41% Lower CPC
Cost per click fell by 41% as ad relevance improved, rewarding the account with better Quality Scores.
Budget Reinvested
Savings were reallocated into higher-performing campaigns, compounding efficiency gains quarter over quarter.
Engagement period · Q1–Q3 2025
Success Story
Optimizing Paths to HCP Engagement
We uncovered a gap between the formal language used across the site and the high-intent questions healthcare professionals were actually searching. By reorganizing the information architecture and aligning clinical assets to real HCP behavior, we made the experience easier to navigate, more relevant and more useful. The result: more qualified organic traffic and more high-value engagement.
- 37% increase in organic users
- 40% increase in prescribing information downloads
Challenge → Solution → Outcome
Specific high-intent phrases didn't match available resources: a disconnect between formal clinical language and the actual queries used by HCPs.
Realigned the site's information architecture and clinical assets to match HCP behavior. Integrated behavioral data science into the creative framework to make the experience more intuitive, relevant, and authoritative.
37% increase in organic users and 40% increase in PEF downloads.
Impact of Relaunch on Engagement
Engagement period · 2023
Success Story
Smarter Bidding (PPC)
Make every claim-controlled campaign work harder and every dollar smarter.
Across a four-brand specialty portfolio, we tightened bidding, expanded negative-keyword coverage and shifted investment toward the audiences most likely to act. This made the campaigns far more efficient, driving the same results for 35.25% less.
Average Cost per Click (CPC) by Brand
Brands reduced CPC
Average CPC reduction
Success Story
AI Overview Optimization
We positioned the brand to answer high-intent consumer questions about the benefits of shelf-stable and DHA-fortified milk.
- Earned the top spot in Featured Snippets and AIO citations.
- Increased engagement by 924% and product interest by 440%.
Connect With Us
Accelerate brand visibility and scale access to your treatments.
Whether the opportunity begins with visibility or nonprescription access, we’ll help you find the clearest next move across Search, AI and ACNU.
contact@idea-evolver.com